Makore served as one of Morgan Tsvangirai’s closest aides before the Government of National Unity (GNU) was formed. He was a director in Tsvangirai's office up until 2007 when he decided to run for political office. Makore contested and won the Chitungwiza Senator post on an MDC ticket in March 2008.
Makore is a war veteran who trained in Zimbabwe, Zambia and Namibia. He was later responsible for recruiting ZANLA cadres. He said he remained in Zanu PF after Independence up until 1997. Asked why he left Zanu-PF, Makore referred to Zimbabwe's involvement in the war in DRC as one of the reasons he left. He said:
"There were areas of disagreements, labour issues, external wars etc."
Makore is one of the trade unionists from the ZCTU who joined hands with Tsvangirai and many others to form the MDC. He served as overall coordinator in 1999, then as director of organizing in 2001, rising to become a director in Tsvangirai's office.
As Senator for Harare, Makore chaired the Portfolio Committee on Women, Gender and Community Development and the Thematic Committee on Gender.
Leaving MDC Alliance
Rejoining Zanu PF
On 17 March 2021, Makore and Obert Gutu joined Zanu PF. The two met Emmerson Mnangagwa and Constantino Chiwenga at State House in Harare. The meeting was also attended by Zanu PF national chair Oppah Muchinguri-Kashiri, Ezra Chadzamira and Lovemore Matuke. Prior to joining Zanu PF, Makore and Gutu had served as members of the MDC-T.
- Swear in Makore, demands MDC, The Zimbabwean, Published: September 27, 2011, Retrieved: March 17, 2021
- Veneranda Langa, Women’ rights groups plead with Parly over Gender Commission independence, NewsDay;;, Published: May 5, 2015, Retrieved: March 17, 2021
- Christopher Makaza, MDC bigwigs dump Chamisa, Harare Post, Published: April 28, 2020, Retrieved: March 17, 2021
- Farirai Machivenyika, JUST IN: Obert Gutu and James Makore join Zanu-pf, The Herald, Published: March 17, 2021, Retrieved: March 17, 2021